烧伤患者中COVID-19相关的候群病的特征
Maryam Salimi1,2, Javad Javidnia2,3, Azam Moslemi1,2
1Student Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Journal of clinical laboratory analysis
|April 8, 2025
概括
在ICU中,COVID-19和候选血症构成重大风险,特别是在烧伤患者中. 殖民化,长期住院和导管使用是侵袭性坎迪达菌感染的关键风险因素,耐药性越来越令人担忧.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 菌类学 菌类学是指菌类学.
背景情况:
- 随着COVID-19的流行,候选病的发病率增加.
- 坎迪达菌种是重症监护室 (ICU) 中死亡的重要原因之一.
- 在ICU中的COVID-19烧伤患者是真菌感染的脆弱人群.
研究的目的:
- 在ICU中的COVID-19烧伤患者中调查Candida感染的危险因素.
- 评估来自该患者组的Candida分离物的体外抗真菌敏感性.
- 确定Candida殖民的预后意义.
主要方法:
- 研究了56名同时患有COVID-19并入ICU的烧伤患者.
- 酵母分离物从烧伤,血液和尿液培养物中获得.
- 使用聚合酶连锁反应-限制片段长度多态性 (PCR-RFLP) 分析进行了分离物鉴定.
主要成果:
- 鉴定到的最常见的物种是Candida parapsilosis.
- 感染患者 (69.0%) 与殖民患者 (43.8%) 的死亡率更高.
- 卢利可纳和安福特里辛B在体外对Candida分离物的疗效最高.
结论:
- 坎迪达菌种植可能会预测严重病情的烧伤患者的随后的坎迪迪达病.
- 长时间住院,导管使用和COVID-19是候选血症的重要危险因素.
- 增加非白虫Candida物种的抗真菌药物耐药性是一个关键的公共卫生问题.
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