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Updated: Apr 28, 2026

Combining Intravital Fluorescent Microscopy IVFM with Genetic Models to Study Engraftment Dynamics of Hematopoietic Cells to Bone Marrow Niches
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通过VavCre介导的Gbe删除,在高氏病中建模骨髓微环境和造血失调

Glenn Belinsky1, Jiapeng Ruan1, Nima Fattahi1

  • 1Department of Medicine (Digestive Diseases), Yale School of Medicine, The Anylan Center, 300 Cedar St, New Haven, Connecticut 06519, United States.

Human molecular genetics
|April 8, 2025
PubMed
概括

一种新的小鼠模型,具有造血特异性Gba淘汰,被开发用于研究高氏病 (GD). 该模型揭示了遗传背景影响GD严重程度和免疫系统变化,有助于生物标志物发现.

关键词:
骨髓的微环境 骨髓的微环境戈舍氏病是戈舍氏病的一种疾病.这是一个VavCre鼠标模型.免疫调节失调 免疫调节失调骨质结核病的结核病.

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