暴露前预防:克服吸收和持久性障碍的临床考虑
Nathaniel Albright1,2,3, Adam Leonard1,2,3, Alanna J Bergman1,2,3
1Nathaniel Albright, MSN, RN, FNP-BC, AAHIVS, is a doctoral candidate, Ohio State University College of Nursing, Columbus, Ohio, USA.
概括
暴露前预防 (PrEP) 可以预防艾滋病毒感染. 解决PrEP吸收和持续存在的障碍对艾滋病毒流行病战略至关重要,需要为优先人群提供多层次解决方案.
科学领域:
- 公共卫生 公共卫生
- 预防传染病 预防传染病
- 艾滋病毒/艾滋病研究研究
背景情况:
- 暴露前预防 (PrEP) 是预防艾滋病毒感染的关键策略.
- 目前的PrEP选择包括口服和长效注射抗逆转录病毒药物.
- 尽管它是有效的,但在那些可能受益的人群中,PrEP的吸收和持续性仍然不够理想.
研究的目的:
- 在优先人群中识别PrEP护理的障碍.
- 讨论以证据为基础的解决方案,以改善PrEP获取和遵守.
- 为增加PrEP使用量提出多层次考虑.
主要方法:
- 审查关于PrEP障碍物和促进剂的现有文献.
- 影响PrEP吸收和持续性的社会生态因素的分析.
- 综合基于证据的干预措施和策略.
主要成果:
- 阻碍PrEP护理的障碍是复杂的,跨越个人,人际,社区和结构层面.
- 优先人群在获得和坚持PrEP方面面临着独特的挑战.
- 需要多层次的干预措施来解决这些多方面的障碍.
结论:
- 克服PrEP的障碍需要一个全面的方法,涉及临床医生,研究人员和社区.
- 实施基于证据的解决方案可以提高prep的吸收和持续性.
- 增加对PrEP的获取和持续使用对于结束艾滋病毒流行病至关重要.
相关概念视频
Transmission-based Precautions II: Airborne and Protective Environment
1.2K
Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
1.2K
Desensitization and Tachyphylaxis
1.4K
Tachyphylaxis is described as a rapid decrease in response to a drug after repeated or continuous administration of the same drug dose. It is a phenomenon where the body becomes less responsive to a particular substance or intervention over time, requiring higher doses or stronger interventions to achieve the same effect. It results from adaptive changes in the body's receptors, signaling pathways, or physiological processes that occur in response to prolonged exposure to a stimulus.
1.4K
Transmission-based Precautions I: Contact, Enteric, and Droplets
3.2K
Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
3.2K
Pulmonary Tuberculosis V
157
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
157
Healthcare Associated Infections II: Preventive Measures
2.3K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.3K
Infection
6.6K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
6.6K


