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Updated: May 20, 2025

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泰利多米德诱导的四肢形:更新和重新评估

Michael D Collins1, William J Scott2

  • 1Department of Environmental Health Sciences and Molecular Toxicology Interdisciplinary Program, UCLA School of Public Health, CHS 46-078, 650 Charles E. Young Drive South, Los Angeles, CA, 90095, USA. mdc@ucla.edu.

Archives of toxicology
|April 8, 2025
PubMed
概括

塔利多米德在发育中的胚胎中引起肢体形,主要影响前肢和左肢. 大脑结机制解释了这种胚性病变,SALL4作为一个关键的新基质.

关键词:
异构体 异构体 异构体 异构体 异构体 异构体身体的各个部分.一个复印件 (phenocopy) 是一个复印件.福基米利亚 (Phocomelia) 是一种有机物.在 SALL4 中,你会发现品种的特异性 品种的特异性泰利多胺是一种

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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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