在非病理性近视症与异观近视症中,眼内比较了周周状视网膜神经纤维层厚度和血管结构
Yafei Mu1, Maierhaba Mijiti1, Wei Wei1
1Opthalmic Center, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, 830001, China.
概括
在异视近视的眼睛中,时间周状视网膜神经纤维层 (RNFL) 在更近视的眼睛中较厚. 这些变化可能会在病态近视发展之前发生.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜成像 视网膜成像
- 近视研究 近视研究
背景情况:
- 异度失明,眼睛之间有不平等的折射误差,在近视中很常见.
- 了解异质的眼睛参数差异对于早期检测潜在的病理变化至关重要.
研究的目的:
- 在非病理性近视患者中调查周周毛囊视网膜神经纤维层 (RNFL) 厚度和视网膜血管结构的整眼差异.
- 为了将这些差异与异构度的程度相关联.
主要方法:
- 对50名11-40岁的参与者 (100只眼睛) 进行了回顾性横截面研究,他们患有异度近视.
- 使用Cirrus光谱域光学连贯断层扫描 (SD-OCT) 检测RNFL厚度,视神经头部 (ONH) 参数,斑点血管密度 (MVD),光盘血管密度 (OVD) 和光盘 perfusion密度 (OPD).
- 参与者按整眼球体等效 (SE) 差异分组:>1.50 D (第一组) 和1.001.50 D (第二组).
主要成果:
- 在更近视的眼睛中,周囊RNFL较厚;上部和下部RNFL较薄.
- 时间RNFL厚度,鼻腔MVD,时间/下部OVD和时间OPD的眼内差异与整眼SE和轴长度 (AL) 差异相关.
- 第1组与第2组相比,时间RNFL厚度,OVD和OPD的整眼差异更为显著.
结论:
- 时间周囊RNFL加厚,以及较高的OVD和OPD,在异视眼中观察到更多的近视眼睛.
- 这些区域血管和RNFL变化可能表明RNFL稀释和病态近视发作之前的早期变化.
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