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一个有针对性的CRISPR屏幕将ETS1识别为HIV-1潜伏时间的调节者

Manickam Ashokkumar1,2, Terry L Hafer3,4, Abby Felton3,4

  • 1Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.

PLoS pathogens
|April 8, 2025
PubMed
概括

转录因子ETS1通过抑制MALAT1和调节病毒LTR中的基因组修饰来维持人类免疫缺陷病毒-1 (HIV-1) 延迟. 在ETS1中,ETS1是ETS1.

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