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Updated: May 15, 2025

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两种自动化胰岛素输送系统在1型糖尿病成年人中的长期性能:一项观察性研究
Sanne Fisker1, Mia Christensen2, Ermina Bach1,3
1Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark.
Endocrinology, diabetes & metabolism
|April 8, 2025
概括
与MiniMed 780G (MM780G) 系统相比,Tandem Control IQ (CIQ) 系统显示出较高的葡萄糖传感器磨损,但范围内的时间较短 (TIR) 和范围较窄 (TITR).
科学领域:
- 内分泌学 在内分泌学.
- 糖尿病 技术 技术
- 代谢健康 代谢健康
背景情况:
- 自动注射胰岛素 (AID) 系统旨在改善1型糖尿病的血糖控制.
- 对比不同的AID系统对于优化患者的治疗结果至关重要.
研究的目的:
- 为了比较Tandem Control IQ (CIQ) 和MiniMed 780G (MM780G) 自动化胰岛素输送系统的血糖结果.
主要方法:
- 一项观察性研究评估了来自139名1型糖尿病患者的60天的血糖数据.
- 参与者使用CIQ (n=79) 或MM780G (n=60) 系统,活性葡萄糖传感器时间≥85%.
主要成果:
- 该CIQ系统显示活性葡萄糖传感器时间更长 (98.5% vs 96.5%,p<0.001).
- 然而,CIQ用户在范围内的时间 (TIR) (68.9%与73.7%,p=0.02) 和在狭窄范围内的时间 (TITR) (43.0%与48.4%,p=0.01) 与MM780G用户相比较短.
- CIQ还显示了较快的葡萄糖变化速度 (9.4%与7.4%,p<0.001) 的时间更长.
结论:
- CIQ系统实现了更高的葡萄糖传感器利用率,但导致TIR和TITR减少.
- MM780G系统在目标范围内显示出优异的血糖控制.
- 在控制基线变量后,TIR和TITR的差异仍然很大.
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