在年轻的门诊患者群体中,螺旋计变化及其危险因素
Marc Vila1, Sandra Casas-Recasens2, Rosa Faner3
1Equip d'Assistència Primària Vic (EAPVIC), Barcelona, España; Grup de recerca Methodology, Methods, Models and Outcomes of Health and Social Sciences (M(3)O); Facultat de Ciències de la Salut i el Benestar. Universitat de Vic-Universitat Central de Catalunya (UVic-UCC), Barcelona, España; Càtedra Salut Respiratòria, Universitat de Barcelona, Barcelona, España.
Medicina clinica
|April 8, 2025
概括
奥索纳的年轻人显示出高频率的异常螺旋测量,反映了30多年前的发现. 这表明该地区存在持续的呼吸系统健康问题,需要进一步调查.
科学领域:
- 肺部医学 肺部医学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 年龄在20-40岁的成年人中降低的螺旋计值与呼吸道和非呼吸道疾病和死亡率的风险增加有关.
- 30多年前的一项先前的研究 (IBERPOC) 发现,在西班牙奥索纳的40岁以上的成年人中,慢性阻塞性肺病 (COPD) 的患病率很高 (18%).
研究的目的:
- 为了确定目前的螺旋测量变化的流行情况.
- 确定与这些变化相关的临床表现和风险因素.
- 评估奥索纳地区18-50岁成年人的呼吸系统健康状况.
主要方法:
- 前性研究包括241名参与者 (61.8%的女性,38.2%的男性),年龄在18-50岁,居住在奥索纳.
- 在支气管扩张之前进行了螺旋计.
- 收集有关呼吸道症状,病史和潜在风险因素的数据.
主要成果:
- 20.7%的研究人群表现出螺旋计异常 (FEV1,FVC或FEV1/FVC低于正常的下限).
- 异常的螺旋测量在男性中更为普遍,特别是那些吸烟和从事高风险职业的人.
- 20-30%的参与者报告呼吸道症状,女性更频繁.
- 与正常的精神检测相比,精神检测异常的个体诊断的慢性肺炎,喘或糖尿病的发病率较高,吸烟暴露或早期生活事件没有差异.
结论:
- 在奥索纳的年轻成年人中,精神测量值异常的患病率仍然很高,为20.7%,与30多年前的发现一致.
- 这些螺旋测量异常的持续存在表明该地区正在进行的潜在问题.
- 建议对环境,遗传和表观遗传因素进行进一步的研究,以了解这些发现的起源.
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