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大气沉颗粒物对太平洋白Litopenaeus vannamei的生化和细胞遗传影响

F Copetti¹, C R Nobre², M S Paço²

¹Institute of Biosciences, São Paulo State University "Júlio de Mesquita Filho", Litoral Paulista Campus, Infante Dom Henrique Square, s/n - Parque Bitaru, São Vicente, São Paulo 11330-900, Brazil.

Aquatic toxicology (Amsterdam, Netherlands)

|April 8, 2025

概括

炼业对大气的排放损害了太平洋白 (Litopenaeus vannamei) 的细胞损伤. 即使低度的可沉降颗粒物 (SePM) 也会损害的健康,威胁到水产养殖的可持续性.

科学领域:

环境毒理学环境毒理学
水生物质毒理学研究
海洋生物学海洋生物学

背景情况:

金工业对大气的排放会释放出微小和纳米粒子.
这些颗粒,特别是可沉大气颗粒物 (SePM),可以进入水生生态系统.
太平洋白 (Litopenaeus vannamei) 是水产养殖和河口环境中的一个关键物种.

研究的目的:

调查金SePM对Litopenaeus vannamei.的次致命影响.
评估细胞毒性 (淋巴体膜稳定性 - LMS),脂质过氧化 (LPO),基因毒性 (DNA链断裂) 和神经毒性 (乙胆酶活性 - AChE).
为了确定环境相关的SePM度和暴露时间对组织的影响.

主要方法:

被暴露在三种度 (0.001,0.1,1.0 g.L-1) 的SePM.
暴露时间包括T2,T4,T7,T15和T30天.
细胞损伤的生物标志物 (LMS,LPO,DNA链断裂,ACHE) 在,血淋巴,肌肉和肝中进行了分析.

主要成果:

脂质过氧化 (LPO) 和溶酶体膜稳定性 (LMS) 在暴露的前两天内显示出显著的变化.
从第7天到第15天,在0.1g.L-1.1的度下观察到显著的效应.
到第30天,所有测试的SePM度都在组织中诱导了细胞毒性,表明了病变前状态.

结论:

暴露于金SePM会在Litopenaeus vannamei中引起显著的细胞功能障碍.
这些发现凸显了大气颗粒物对健康和水产养殖的潜在风险.
有效的监测和缓解策略对于可持续的水产养殖实践至关重要.

关键词:

金属颗粒是一种金属颗粒.类是什么意思?类是什么意思?潜致死的影响.毒理学潜在的毒理潜力热带河口的热带河口

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