阿里皮普拉的与哺乳相关的副作用:印度围产期精神病学服务机构的一项研究
Madhuri H Nanjundaswamy1, Aana Shah2, Shraddha Lotlikar1
1From the Department of Psychiatry, National Institute of Mental Health and Neurosciences Bangalore.
Journal of clinical psychopharmacology
|April 8, 2025
概括
大多数在产后继续服用阿里皮普拉 (一种节省乳糖的抗精神病药物) 的女性经历了哺乳失败或乳生产不足. 与孕妇讨论这些哺乳期问题至关重要.
科学领域:
- 围产阶段精神病学 围产阶段精神病学
- 药理学 药理学是指药理学的学科.
- 哺乳期研究 哺乳期研究
背景情况:
- 阿里皮普拉是一种节省益生素的抗精神病药物,在怀孕期间被认为是安全的,具有良好的代谢特征.
- 关于阿里皮普拉对产后哺乳的影响的数据有限.
- 这项研究研究了怀孕期间和产后对哺乳期结果的阿里皮普拉使用情况.
研究的目的:
- 评估在怀孕期间和产后使用阿里皮普拉与哺乳期结果之间的关系.
- 为了确定乳房衰竭或乳房不足在使用阿里皮普拉的妇女的发生率.
主要方法:
- 对参加围产期精神病学服务的妇女的回顾性图表审查 (2016年1月 - 2021年12月).
- 收集关于阿里皮普拉处方,临床信息和哺乳期结果的数据.
- 哺乳衰竭被定义为至少7天的完全缺乏或最小的乳液分泌.
主要成果:
- 35名在分娩后继续服用阿里皮普拉的妇女有可用的哺乳数据.
- 74% (26/35) 的人经历了完全的哺乳失败.
- 11% (4/35) 在服用阿里皮普拉时 (平均剂量为16.4毫克/天) 没有足够的牛奶产量.
结论:
- 在怀孕和产后期间使用阿里皮普拉与高乳房衰竭或乳房不足率有关.
- 服用阿里皮普拉的妇女应就潜在的哺乳问题得到咨询.
- 需要进一步的研究才能充分了解阿里皮普拉对哺乳期的影响.
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