Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

680
In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
680
Glial Cells01:04

Glial Cells

85.7K
Overview
85.7K
Nervous Tissue: Glial Cells01:31

Nervous Tissue: Glial Cells

2.4K
Glia, or neuroglia, are vital support cells that assist neurons in their functions. The term "glia" originates from the Greek word for "glue," reflecting their role in holding the nervous system together. These cells can be categorized into six types: four in the central nervous system (CNS) and two in the peripheral nervous system (PNS).
The CNS glial cell includes the astrocytes, the oligodendrocytes, the microglia, and the ependymal cells.
Astrocytes are star-shaped glial...
2.4K
Neural Regulation01:37

Neural Regulation

39.0K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
39.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Causal Relationship Between Gut Microbiota and Chronic Obstructive Pulmonary Disease: A Bidirectional Two-Sample Mendelian Randomization Study.

International journal of chronic obstructive pulmonary disease·2024
Same author

Translational evaluation of metabolic risk factors impacting DBS efficacy for PD-related sleep and depressive disorders: preclinical, prospective and cohort studies.

International journal of surgery (London, England)·2024
Same author

Atrial tachyarrhythmia prevention by Shensong Yangxin after catheter ablation for persistent atrial fibrillation: the SS-AFRF trial.

European heart journal·2024
Same author

A nomoscore of four genes for predicting the rupture risk in abdominal aortic aneurysm patients with osteoarthritis.

Gene·2024
Same author

Author Correction: Deep brain stimulation of symptom-specific networks in Parkinson's disease.

Nature communications·2024
Same author

The traditional Chinese medicine Qiliqiangxin in heart failure with reduced ejection fraction: a randomized, double-blind, placebo-controlled trial.

Nature medicine·2024

相关实验视频

Updated: May 15, 2025

Culturing Microglia from the Neonatal and Adult Central Nervous System
11:28

Culturing Microglia from the Neonatal and Adult Central Nervous System

Published on: August 9, 2013

27.8K

周围神经系统的微状细胞在整个进化过程中调节神经元的体积

Zhisheng Wu1, Yiheng Wang2, Wei-Wei Chen3

  • 1Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China; Department of Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China; School of Chemistry and Chemical Engineering, Center of Interventional Radiology and Vascular Surgery, Nurturing Center of Jiangsu Province for State Laboratory of AI Imaging & Interventional Radiology, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.

Cell
|April 8, 2025
PubMed
概括

研究人员发现了外围神经系统 (PNS) 微状细胞,对于神经元大小和功能至关重要. 这些细胞与中枢神经系统 (CNS) 微质细胞相似,对神经元发育和进化至关重要.

关键词:
皮质神经系统的微质演变的过程巨细胞微质细胞微状细胞微质血统神经元的发育神经元总体大小周围微质细胞周围神经系统

更多相关视频

Isolation and Culture of Rodent Microglia to Promote a Dynamic Ramified Morphology in Serum-free Medium
12:00

Isolation and Culture of Rodent Microglia to Promote a Dynamic Ramified Morphology in Serum-free Medium

Published on: March 9, 2018

15.8K
Isolation of Cortical Microglia with Preserved Immunophenotype and Functionality From Murine Neonates
09:12

Isolation of Cortical Microglia with Preserved Immunophenotype and Functionality From Murine Neonates

Published on: January 30, 2014

15.7K

相关实验视频

Last Updated: May 15, 2025

Culturing Microglia from the Neonatal and Adult Central Nervous System
11:28

Culturing Microglia from the Neonatal and Adult Central Nervous System

Published on: August 9, 2013

27.8K
Isolation and Culture of Rodent Microglia to Promote a Dynamic Ramified Morphology in Serum-free Medium
12:00

Isolation and Culture of Rodent Microglia to Promote a Dynamic Ramified Morphology in Serum-free Medium

Published on: March 9, 2018

15.8K
Isolation of Cortical Microglia with Preserved Immunophenotype and Functionality From Murine Neonates
09:12

Isolation of Cortical Microglia with Preserved Immunophenotype and Functionality From Murine Neonates

Published on: January 30, 2014

15.7K

科学领域:

  • 神经科学
  • 免疫学
  • 进化生物学

背景情况:

  • 微细胞是中枢神经系统 (CNS) 中的主要免疫细胞.
  • 从历史上看,微质被认为不在外周神经系统 (PNS) 中.

研究的目的:

  • 识别和描述PNS中的新型巨细胞群.
  • 研究这种PNS细胞群的起源,功能和进化意义.

主要方法:

  • 对PNS巨细胞进行转录和表观遗传分析.
  • 在24种脊椎动物中进行了基因分析.
  • 关于神经元发育和大小调节的功能研究.

主要成果:

  • 鉴定出一种称为PNS微状细胞的PNS巨细胞群.
  • 这些细胞与中枢神经系统的微细胞具有共同的分子和发育特征.
  • 类似PNS微细胞调节神经元体大小和轴突生长,它们的存在与脊椎动物的神经元体大小相关.

结论:

  • 这项研究揭示了PNS对应的中枢神经质.
  • 在发育和进化过程中,PNS微状细胞在调节神经元体大小方面发挥着关键作用.
  • 这些发现重新定义了神经系统中微相关细胞的分布和功能.