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Updated: Jul 15, 2026

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[对于谁,如何和为什么目的 - 结直肠癌的新辅助疗法?]

Franziska Willis1, Thilo Schwandner2, Martin Reichert1

  • 1Abteilung für Allgemein-, Viszeral-, Thorax- und Transplantationschirurgie, Universitätsklinikum Gießen und Marburg, Standort Gießen, Gießen, Deutschland.

Zentralblatt fur Chirurgie
|April 8, 2025
PubMed
概括

新辅助疗法改善了直肠癌的治疗结果. 研究正在探索全新辅助疗法 (TNT) 和器官保存策略,以进一步优化基于癌症阶段的个性化治疗.

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.