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Updated: May 15, 2025

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代优化产生了具有优越药理动力学和纤维化治疗功效的合

Bochuan Deng1, Ping Su1, Lu Cheng2

  • 1Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences & Research Unit of Peptide Science, Chinese Academy of Medical Sciences, 2019RU066, Lanzhou University, Lanzhou 730000, China.

Journal of medicinal chemistry
|April 8, 2025
PubMed
概括

研究人员优化了DR3penA,制造了27,这是纤维化潜在的新疗法. 这种增强的显示出更好的稳定性,并有效地向纤维细胞,为患有脏疾病的患者提供希望.

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Heart Failure Drugs: Inhibitors of Renin-Angiotensin System01:26

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
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