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Updated: May 15, 2025

In Vitro and In Vivo Approaches to Determine Intestinal Epithelial Cell Permeability
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梅特林通过IKKβ/IκBα/NFκB/MLC/MLC信号通路调节紧密的接口来保护肠道屏障功能

Zhi-Yong Li1,2, Heng-Yu Luo3, Fei Xu3

  • 1Department of Pharmacology, Second Military Medical University/Naval Medical University, Shanghai, 200433, China. zhiyongli@smmu.edu.cn.

Cell death discovery
|April 8, 2025
PubMed
概括

流星类 (Metrnl) 蛋白通过抑制NFκB通路来保护肠道屏障的完整性. 梅特林缺乏会破坏紧密的结节,而梅特林的使用或过度表达会保持屏障功能并缓解结肠炎.

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