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Updated: May 15, 2025

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
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识别英多尔作为ERRγ的潜在内源配体及其对药物结合的调制

Yuan-Yuan Shuai1,2, Hong-Yang Zhang3,4, Rui Chen2

  • 1Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230026, China.

Acta pharmacologica Sinica
|April 8, 2025
PubMed
概括

肠道细菌产生醇和醇,被确定为雌激素相关受体 γ (ERRγ) 的潜在内源配体. 这些化合物与ERRγ结合,影响其活性,并表明肠道微生物群与能量代谢调节之间的联系.

关键词:
在ERRγ ERRγ这是内源性联结体.印度尔 (Indole) 是一种制剂.代谢产物的代谢产物核受体是核受体的一个组成部分.

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