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Updated: May 22, 2025

Simultaneous Measurement of Mitochondrial Calcium and Mitochondrial Membrane Potential in Live Cells by Fluorescent Microscopy
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TMEM65调节并对NCLX依赖的线粒体流量有必要

Joanne F Garbincius1, Oniel Salik1, Henry M Cohen1

  • 1Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.

Nature metabolism
|April 8, 2025
PubMed
概括

线粒体蛋白TMEM65通过NCLX交换器调节 (Ca2+) 流量. 丧失TMEM65功能会导致过载和器官功能障碍,这表明TMEM65是治疗点.

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