亚洲的胃肠道癌症负担,1990-2019年
Chengwei Xia1, Yini Liu2, Xin Qing3
1Department of Thyroid & Breast Surgery, Chengdu Seventh People's Hospital (Affiliated Cancer Hospital of Chengdu Medical College), Chengdu, China.
BMC gastroenterology
|April 8, 2025
概括
胃肠道 (GI) 癌症仍然是亚洲的一个重大健康问题. 虽然绝对数字增加,但发病率和死亡率的趋势因癌症类型和人口统计学而异,受生活方式风险因素的影响.
科学领域:
- 流行病学 流行病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 胃肠道 (GI) 癌症对全球的健康构成重大负担.
- 在亚洲缺乏对胃肠道癌症的全面流行病学评估.
- 了解区域差异对于有针对性的干预至关重要.
研究的目的:
- 对亚洲6种常见的胃肠道癌进行全面的流行病学评估.
- 分析1990年至2019年的发病率和死亡率的趋势.
- 确定与胃肠道癌负担的人口和风险因素关联.
主要方法:
- 使用全球疾病负担研究 (1990-2019) 数据的流行病学研究.
- 结直肠,食道,胆囊和胆道 (GBTC),肝脏,胰腺和胃癌的发病率和死亡率计算.
- 数据按性别,年龄,年龄,位置和风险因素分层.
主要成果:
- 在2019年,年龄标准化发病率 (ASIR) 从2.77 (GBTC) 到23.88 (结肠直肠),年龄标准化死亡率 (ASDR) 从2.53 (GBTC) 到14.67 (胃).
- 食道,肝脏和胃癌的发病率和死亡率趋势呈上升趋势,而结肠直肠,GBTC和胰腺癌的发病率下降.
- 这种负担在男性和老一代中更高,在地理位置上有所不同,并且与饮食,吸烟,酒精和高BMI有关.
结论:
- 胃肠道癌仍然是亚洲瘤负担的主要原因之一.
- 绝对的胃肠道癌症数量有所上升,但年龄标准化率在过去三十年中显示出不同的趋势.
- 地理和人口差异凸显了亚洲需要量身定制的公共卫生战略.
更多相关视频
相关概念视频
Targeted Cancer Therapies
7.4K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.4K
Cancer Survival Analysis
308
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
308


