相关实验视频

Updated: May 15, 2025

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
11:06

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro

Published on: January 31, 2022

4.2K

肝毒性门户网站 (HTP):是药物诱导肝毒性知识库和基于图形神经网络的预测模型的综合数据库

Jiyeon Han1, Wonho Zhung2, Insoo Jang3

  • 1Department of Bio-Information Science, Ewha Womans University, Seoul, 03760, Republic of Korea.

Journal of cheminformatics
|April 8, 2025
PubMed
概括

一个新的肝毒性门户 (HTP) 提供精选的肝毒性数据和先进的机器学习模型,用于准确的药物开发预测. 该工具整合了各种数据源,以改善药物安全性评估.

关键词:
深度神经网络是一个神经网络.药物诱导的肝损伤是药物诱导的肝损伤.精细调整 微调 精细调整基金会模型 基金会模型图表神经网络的神经网络肝毒性 肝毒性 肝毒性肝脏毒性 肝脏毒性分子图谱 分子图表

更多相关视频

Predicting Treatment Response to Image-Guided Therapies Using Machine Learning: An Example for Trans-Arterial Treatment of Hepatocellular Carcinoma04:09

Predicting Treatment Response to Image-Guided Therapies Using Machine Learning: An Example for Trans-Arterial Treatment of Hepatocellular Carcinoma

Published on: October 10, 2018

8.2K
A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions07:40

A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions

Published on: May 27, 2021

4.1K

相关概念视频

Physiological Pharmacokinetic Models: Incorporating Hepatic Transporter-Mediated Clearance01:07

Physiological Pharmacokinetic Models: Incorporating Hepatic Transporter-Mediated Clearance

Drug transporters are critical in drug absorption, distribution, and excretion processes. They should be included in physiological-based pharmacokinetic (PBPK) models, which help predict human drug disposition. However, predicting this is challenging during drug development, especially when liver transport is involved. However, with a realistic representation of body transport processes, an accurate model may be possible.
A recent model describes pravastatin's hepatobiliary excretion,...
20