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Updated: Jul 21, 2026

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通过分子建模研究,对deucravacitinib对TYK2伪激酶与JAK激酶域的选择性进行计算洞察

Manish Ramchandani1, Amit Kumar Goyal1

  • 1Department of Pharmacy, School of Chemical Sciences, Central University of Rajasthan, Ajmer, India.

Journal of biomolecular structure & dynamics
|April 9, 2025
PubMed
概括

德乌克拉维西丁尼通过与其ATP位点结合,选择性地抑制TYK2伪激酶域,为开发具有改进亲和力的新TYK2抑制剂提供了一个有前途的策略.

关键词:
德乌克拉维西提尼布 (Deucravacitinib) 是一种药物.分子对接的分子对接.分子动力学分子动力学伪酶是一种假酶.牛皮是一种牛皮.

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