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Updated: May 15, 2025

Orthogonal Protein Purification Facilitated by a Small Bispecific Affinity Tag
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基于 MabSelect VL 树脂强大的副产品去除能力,用于双特异性抗体净化的一种两列过程

Wanyuan Dong1, Penglong Zhang1, Di Wu1

  • 1Downstream Process Development (DSPD), WuXi Biologics, Shanghai, 200131, China.

Journal of biological methods
|April 9, 2025
PubMed
概括

一种新的蛋白质L树脂,MabSelect VL,可以实现对双特异抗体 (bsAbs) 的简化两列净化过程. 这种精简的方法实现了与传统的三列方法相美的产品质量,从而大大节省了时间和成本.

关键词:
聚合物 聚合物 聚合物双特异性抗体 双特异性抗体在 MabSelect VL 中选择蛋白质A是一种蛋白质.蛋白质 L 是一种蛋白质.三列列的工艺过程.这是双列工艺的过程.

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Immunoprecipitation01:20

Immunoprecipitation

Immunoprecipitation, or IP, is a widely used technique that employs protein-antibody interactions to isolate proteins or protein complexes in their native state for studying protein-protein interactions, quaternary structures, or supramolecular complexes. Various modifications of the technique, including chromatin IP, cross-linking IP, and fluorescence IP, are commonly used.
Chromatin Immunoprecipitation
Chromatin immunoprecipitation, also known as ChIP, is used to study protein-DNA or...
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