泰国的过敏性鼻炎和疹负担和抗组胺药物治疗选择:修改后的德尔菲研究
Hiroshi Chantaphakul1,2, Chirawat Chiewchalermsri3, Dara Mairiang4
1Division of Allergy and Clinical Immunology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
The journal of allergy and clinical immunology. Global
|April 9, 2025
概括
泰国专家更喜欢第二代抗组胺剂用于过敏性鼻炎和慢性疹管理. 改善准则的遵守和药剂师的参与可以减少疾病负担.
科学领域:
- 过敏和免疫学 过敏和免疫学
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 过敏性鼻炎 (AR) 和慢性疹带来了重大的社会经济挑战,特别是在低收入国家.
- 泰国缺乏关于这些过敏状况的全面数据,尽管有可用的基于证据的指南.
- 泰国国内对AR和疹现有指导方针的实施情况各不相同.
研究的目的:
- 描述泰国过敏性鼻炎和疹的当前管理策略.
- 探索有关在泰国临床环境中管理AR和疹的专家共识.
主要方法:
- 泰国过敏,喘和免疫学协会采用了经过修改的Delphi方法.
- 基于网络的问卷收集了来自泰国的105名过敏和免疫学专家的意见.
- 该调查评估了疾病负担,生活质量影响以及对AR和疹的H1-抗组胺使用情况.
主要成果:
- 在88%的管理策略陈述中达成共识.
- 第二代抗胰岛素是首选的AR和疹的初始治疗方法,因为它们具有有利的副作用概况.
- 增加剂量单一抗组胺剂被青的慢性疹,口服分解配方指出易于使用.
结论:
- 泰国临床医生之间存在关于AR和疹的基于证据的实践的知识差距.
- 加强对临床指导方针的遵守,并让药剂师参与,可以改善药物获取和患者的治疗结果.
- 改进的管理策略可以减少泰国过敏性鼻炎和慢性疹的社会经济负担.
更多相关视频
相关概念视频
01:15Upper Respiratory Drugs: First and Second-Generation Antihistamines
155
Antihistamines are a class of drugs widely used to alleviate the symptoms of allergies, such as sneezing, itching, and nasal congestion. They work by inhibiting the actions of histamine, which is released by immune cells in response to allergenic substances or tissue injuries.
Histamine binds to specific receptor sites, known as H1 receptors, on tissue cells, triggering inflammation and swelling. Antihistamines combat these effects by competing with histamine for these receptor sites. By...
Histamine binds to specific receptor sites, known as H1 receptors, on tissue cells, triggering inflammation and swelling. Antihistamines combat these effects by competing with histamine for these receptor sites. By...
155
01:25Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
182
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
182
01:16Drugs Used in Upper Respiratory Disorders: Overview
147
Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
147
02:06Allergic Reactions
27.2K
Overview
27.2K
01:30Asthma-IV: Diagnostic and Management
2.5K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.5K
01:19Antiasthma Drugs: Leukotriene Modifiers
172
Leukotriene modifiers, or cysteinyl leukotriene receptor antagonists, are medications used to manage chronic asthma. These agents target specific inflammatory mediators produced during arachidonic acid metabolism, an essential process in generating inflammation in the body.
Leukotriene modifiers work through two distinct mechanisms:
Leukotriene modifiers work through two distinct mechanisms:
172