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Updated: Jul 27, 2026

In Vivo Photolabeling of Cells in the Colon to Assess Migratory Potential of Hematopoietic Cells in Neonatal Mice
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空间转录学描绘了心脏和古典死性肠球炎肠道表型的潜在差异

Kathryn Y Burge1, Constantin Georgescu2, Hua Zhong1

  • 1Department of Pediatrics, Section of Neonatal-Perinatal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

iScience
|April 9, 2025
PubMed
概括

心脏NEC和经典NEC,新生儿胃肠道疾病,表现出明显的细胞和分子差异. 空间转录学揭示了这些NEC亚型之间的独特的免疫和上皮细胞通路变异.

关键词:
免疫系统的组成部分疾病 疾病 疾病胃肠病学 胃肠病学儿科 儿科 儿科蛋白质组学是指蛋白质组学.文字转录学 (Transcriptomics) 是一个学科.

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Renewal of Intestinal Stem Cells01:23

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The intestinal epithelial lining rapidly renews every 4 to 5 days. The renewal is facilitated by intestinal stem cells (ISCs) located at the base of the crypt– a gland located at the bottom of each villus. ISCs divide asymmetrically to form new stem cells and progenitor daughter cells. The daughter cells are called transit-amplifying (TA) cells which move upwards along the crypt and either differentiate into absorptive cells– the enterocytes or secretory cells– including the goblet,...