含瘦牛肉的地中海式饮食降低血压并改善血管功能:随机交叉试验的二次结果
Jennifer A Fleming1, Kristina S Petersen1, Penny M Kris-Etherton1
1Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA, United States.
Current developments in nutrition
|April 9, 2025
概括
地中海饮食,即使是含有瘦肉的牛肉,与美国平均饮食相比,也改善了血压和动脉硬. 这种饮食模式支持血管健康,没有不良影响.
科学领域:
- 心血管健康 心血管健康
- 营养科学 营养科学
- 饮食模式 饮食模式
背景情况:
- 已知地中海 (MED) 饮食模式可以改善心血管疾病 (CVD) 风险因素.
- 中枢静脉血压升高和动脉硬是心血管疾病的独立预测因素.
- 介质饮食对这些特定血管健康标志物的影响仍然没有被研究.
研究的目的:
- 评估一种MED饮食对血管健康的影响,其中含有不同数量的瘦牛肉 (0.5,2.5和5.5司/日).
- 为了将这些效应与美国平均饮食 (AAD) 进行比较.
- 关键的血管结果包括手臂和中央血压,脉冲波速度 (PWV) 和增强指数.
主要方法:
- 进行了一项多中心,随机,交叉,受控养研究.
- 参与者在随机顺序下4周消耗了每个测试饮食 (MED0.5,MED2.5,MED5.5,AAD).
- 血管结果在基线和每次饮食期间后都被测量,并使用线性混合模型进行分析.
主要成果:
- 在饮食之间观察到周围和中心血压和PWV的显著差异 (P <0.05).
- 与AAD相比,采用0.5和2.5司/天瘦牛肉的MED饮食显示PWV和中央缩血压降低.
- 所有的MED饮食都导致了比AAD更低的手臂缩压和腹缩压.
结论:
- 与AAD相比,MED饮食每天含有多达5.5司瘦牛肉的饮食改善了手臂和中心血压和动脉硬度.
- 这些发现表明,适度含量瘦牛肉的MED饮食不会对血管功能产生负面影响.
- 这项研究已在clinicaltrials.gov (NCT02723617) 注册.
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