药物挑战测试用于早期控制冠状动脉的患者的症状:一个病例报告
Yoshiaki Kawase1, Kento Kikuchi1, Takuya Mizukami1
1Department of Cardiology, Gifu Heart Center, 4-14-4 Yabutaminami, Gifu City, Gifu 500-8384, Japan.
European heart journal. Case reports
|April 9, 2025
概括
对于耐火性冠状动脉 (CAS),传统日本药物shigyakusan和keishibukuryogan的组合,以及标准治疗,有效控制了心痛的症状. 这种方法为难以治疗的CAS患者提供了新的治疗选择.
科学领域:
- 心脏病学 心脏病学
- 药理学 药理学是指药理学的学科.
- 内部医学 内部医学
背景情况:
- 冠状动脉 (CAS) 通常使用通道阻塞剂和长效酸盐来治疗.
- 耐火性CAS病例在一线和二线治疗不足时存在挑战.
- 对于持久性CAS症状的患者,存在有限的治疗选择.
研究的目的:
- 研究新型药物组合对耐火冠状动脉 (CAS) 的疗效.
- 评估日本传统医药在治疗严重CAS症状方面的有效性.
主要方法:
- 一个70岁妇女的案例研究,通过乙胆挑试验诊断出耐火性CAS.
- 四种潜在的药物 (trimetazidine,shigyakusan,keishibukuryogan,denopamine) 的连续使用.
- 评估了用通道阻塞剂,尼科兰迪尔和两种有效的日本传统药物 (石家庄山药,石家庄山药) 的组合疗法.
主要成果:
- 标准治疗 (通道阻断剂和尼科兰迪尔) 对该患者的胸痛无效.
- 石家庄山和石家庄bukuryogan显示了个人的有效性,但单独是不够的.
- 与现有的药物结合使用石家庄山和石家庄古里冈,导致症状得到很好的控制.
结论:
- 药物挑战测试方法可以确定耐火CAS的有效治疗方法.
- 将传统日本药物与标准治疗相结合,为管理困难的CAS病例提供了可行的策略.
- 这一案例凸显了在耐心心血管疾病中整合补充药物的潜力.
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