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估计较高的活微生物饮食摄入量与美国成年人较低的死亡率有关

Xuna Liu¹, Yiwen Wang²

¹Shaanxi Provincial People's Hospital, Xi'an, China.

Frontiers in nutrition

|April 9, 2025

概括

较高的全食摄入活微生物 (TDIIM) 与美国成年人的死亡风险降低有关. 通过饮食消耗更多的活微生物可能会带来显著的健康益处.

科学领域:

微生物学微生物学
营养科学营养科学
流行病学流行病学

背景情况:

关于通过饮食总摄入活微生物 (TDIIM) 的健康益处的研究有限.
调查每日估计的TDIIM与美国成年人死亡率之间的关联对公共卫生至关重要.

研究的目的:

检查估计的活微生物的饮食总摄入量 (TDIIM) 与所有原因和心血管疾病 (CVD) 死亡率之间的关系.
为了确定通过饮食摄入更多的活微生物是否与较低的死亡风险有关.

主要方法:

一项队列研究利用了1999-2018年国家健康和营养检查调查 (NHANES) 的数据,并通过2019年12月31日对死亡率进行了跟踪.
通过将食物分为低,中,高微生物水平,并计算个体摄入量来估计通过饮食摄入的活微生物总量 (TDIIM).
权重考克斯回归,卡普兰-梅尔生存曲线和受限立方线 (RCS) 用于分析死亡率关联.

主要成果:

该研究包括52,383名参与者,在平均118.75个月的随访期间,有7,711例死亡 (1985例心血管疾病死亡).
与较低的TDIIM相比,较高的TDIIM与所有原因死亡率 (HR 0.91) 和心血管疾病死亡率 (HR 0.77) 的风险明显降低.
RCS分析显示,全因死亡率的非线性关系 (摄入量较高的高原) 和心血管疾病死亡率的线性下降趋势.

结论:

估计较高的活微生物的饮食总摄入量 (TDIIM) 与美国成年人全因和心血管疾病 (CVD) 死亡率的降低有关.
这些发现表明,饮食中食用活微生物可能会带来保护性的健康益处.
对特定微生物来源和机制进行进一步的研究是有必要的,以确认这些关联.

关键词:

尼汉斯 (NHANES) 是一个名人.所有原因的死亡率.心血管死亡率心血管死亡率通过饮食摄入活微生物.这是一个前性研究.

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