在怀孕前预测怀孕减肥试验:这是可能的吗?
Jacqueline F Hayes1,2, Suzanne Phelan3, Elissa Jelalian1,2
1Department of Psychiatry and Human Behavior Alpert Medical School of Brown University Providence Rhode Island USA.
Obesity science & practice
|April 9, 2025
概括
在减肥试验中,自我报告的怀孕概率预测了怀孕的可能性,但准确度很低. 需要进一步的方法来改善预先概念研究中对概念的预测.
科学领域:
- 生殖健康 生殖健康
- 临床试验 临床试验
- 行为科学 行为科学
背景情况:
- 预测怀孕对于怀孕前减肥干预试验至关重要.
- 准确的预测有助于试验设计和参与者选择.
研究的目的:
- 评估自我报告的怀孕概率和时间作为怀孕的预测因素.
- 评估这些自我报告的准确性在一个预先概念队列.
主要方法:
- 成年人 (n=184) 超重/肥胖和先前妊娠糖尿病参与了减肥干预或控制.
- 参与者报告了估计的怀孕概率 (1-10) 和预期的基线时间框架.
主要成果:
- 62名参与者 (30%) 在4年内怀孕.
- 怀孕的高概率评级 (8-10) 与更高的受孕率 (45.7%与21.1%) 相关.
- 预测怀孕的高概率评级的灵敏度和特异性分别为69%和58%.
结论:
- 自我报告的怀孕概率是怀孕的预测因素,但其准确性有限.
- 需要使用额外的查方法来改善在预先怀孕试验中的怀孕预测.
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