从2011年到2023年,对澳大利亚西悉尼的B型 estreptococcus细菌病症进行了回顾性审查
Jimmy Shen1, Ravindra Dotel2, Clinton M G Colaco1,3,4
1The University of Sydney, Westmead Clinical School, Sydney, Australia.
IJID regions
|April 9, 2025
目标:
本研究旨在描述一项为期13年的大规模队列研究中B族链球菌(GBS)菌血症的流行病学特征、临床表现、治疗措施及转归。
方法:
这项回顾性研究纳入了2011年1月1日至2023年12月31日期间,在澳大利亚西悉尼四家大都市医院中获得B族链球菌(GBS)血培养阳性的16岁及以上患者。通过电子病历系统对这些阳性培养病例的详细信息进行了回顾。
结果:
在为期13年的研究期间,共纳入344例GBS菌血症患者。患者中位年龄为65岁,50%的患者年龄≥65岁。在83.1%的患者中识别出已知危险因素,其中以心脏病和糖尿病最为常见。皮肤及软组织感染是最常见的首发表现(32.0%)。妊娠相关感染占病例的相当比例(16.3%)。7天和30天死亡率分别为2.3%和5.2%,其中年龄≥65岁患者的死亡率较高,达9.3%。青霉素类是治疗GBS菌血症及其继发表现最常用的抗生素类别(66.1%)。
结论:
GBS 菌血症最常见于年龄 ≥65 岁的个体或孕妇。尽管总体死亡率较低,但在年龄 ≥65 岁人群中死亡率高出两倍。
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