运动训练对心肌梗塞后左心室缩和腹缩功能的影响:系统综述和元分析
XiaoMing Zhang1, Yao Mi2, Mingwang Ding3
1The First Clinical Medical College, Gansu University of Chinese Medicine, Lanzhou, Gansu, China.
在心肌梗塞患者中,运动训练显著改善心脏功能,增强左心室喷射率 (LVEF) 和早期透缩填充 (E). 需要进一步的研究来确认其他心脏指标的益处.
科学领域:
- 心脏病学 心脏病学
- 运动生理学 运动生理学
- 康复医学 康复医学 康复医学
背景情况:
- 运动训练是心肌梗塞 (MI) 康复的患者的关键康复策略.
- 目前关于运动干预改善心脏功能后心脏病发作的有效性的证据有限,需要综合.
- 标准的药理疗法是心脏病发作管理的基石,但它对心脏重塑的影响可以通过运动来增强.
研究的目的:
- 在心肌梗塞患者中进行元分析,评估运动训练在改善心脏功能方面的有效性.
- 综合现有研究的发现,以提供对运动对特定心脏参数的影响的定量评估.
- 为了确定哪些心脏功能指标受到MI后运动训练的影响最为显著.
主要方法:
- 在主要的数据库中进行了系统的文献搜索:PubMed,Embase,Cochrane图书馆和Web of Science.
- 包括比较心脏功能在MI患者接受运动训练加标准治疗与单独标准治疗的研究.
- 评估的关键心脏功能指标包括左心室喷射率 (LVEF),早期透静填充 (E),E/A比率等.
主要成果:
- 分析包括12项研究,包括922名被诊断患有心肌梗塞的患者.
- 运动训练显示左心室喷射率 (LVEF) 在统计学上显著改善 (MD = 3.99,95% CI: 1.30-6.68).
- 此外,早期透心填充 (E) (MD = 3.86,95% CI: 1.33-6.39) 的显著改善也被观察到,而其他评估的心脏指标没有显著改善.
结论:
- 运动训练,当与标准的药理疗法相结合时,为心肌梗塞后患者的心脏功能的特定方面提供了显著的好处.
- 在LVEF和早期的透析填充 (E) 的改善表明,运动对心室性能和放松有积极的影响.
- 需要进一步的研究,以探索运动训练对更广泛的心脏参数和心脏中风幸存者的长期结果的影响.
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