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Updated: May 15, 2025

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睡眠时间与冠心病风险之间的性别相关性:系统性审查和元分析
Cun Li1, Shun-Xin Luo1, Tian-Wei Liang1
1School of Clinical Medicine, Dali University, Dali, Yunnan, China.
Frontiers in cardiovascular medicine
|April 9, 2025
概括
睡眠时间对男性和女性冠心病 (CHD) 风险的影响不同. 这次元分析发现了一个U形风险曲线,最佳睡眠范围因性别而异,以尽量减少心血管疾病.
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 流行病学 流行病学
背景情况:
- 极端睡眠持续时间对其对冠心病 (CHD) 风险的影响进行了辩论.
- 了解睡眠对心血管疾病的性别特异性影响对于公共健康至关重要.
研究的目的:
- 调查睡眠时间与心脏病风险之间的非线性关系.
- 探索该协会中潜在的性别差异.
主要方法:
- 17项观察性研究的元分析,共计906908名参与者.
- 用于趋势和剂量反应分析,使用了通用最小方形和受限立方线模型.
- 层次回归评估了线性剂量-反应关系.
主要成果:
- 在两种性别中都观察到睡眠时间和心脏病风险之间存在显著的U形非线性关系 (P < 0.01).
- 较短的睡眠增加了女性的冠心病风险;较长的睡眠对男性来说带来了更大的风险.
- 最佳睡眠时间为男性7.08.0小时,女性7.58.5小时.
结论:
- 睡眠时间对心血管疾病风险的影响在很大程度上取决于性别.
- 根据性别定制睡眠建议可能是有效预防心脏病的必要条件.
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