中年和老年男性的全身免疫炎症指数和血清丸激素和自由丸激素之间的关联
Liang Su1, Si-Zheng Zhang1, Hao-Yang Cheng1
1Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Andrology
|April 9, 2025
概括
这项研究发现,较高的系统性免疫炎症指数 (SII) 与中年和老年男性的较低和自由水平有关. 这种关联在60岁及以上的男性中对FT特别强烈.
科学领域:
- 内分泌学 在内分泌学.
- 免疫学 免疫学 免疫学
- 老年学是指老年学的学科.
背景情况:
- 慢性炎症在衰老中很常见,可能会影响老年男性的丸激素水平.
- 系统性免疫炎症指数 (SII) 是一种新的炎症生物标志物.
- 了解炎症和丸激素之间的关系对于男性健康至关重要.
研究的目的:
- 为了调查SII和血清丸激素水平之间的关联.
- 为了检查SII和自由 (FT) 水平之间的关联.
- 为了探索这些协会中年和老年男性.
主要方法:
- 来自国家健康和营养检查调查 (2011-2016,2021-2023) 的40岁以上的5354名男性的数据分析.
- 利用多变量回归来评估SII和/FT之间的关系.
- 根据年龄进行了子组分析.
主要成果:
- 在整体队列中观察到SII和血清丸激素和FT之间存在显著的反向关联.
- 较高的SII四分位数与较低的血清丸激素水平相关.
- 在60岁及以上的男性中,SII与FT有显著的反向关联.
结论:
- 这项研究表明,中年和老年男性的SII和/FT之间存在反向关系.
- 这种关联,特别是FT,在60岁及以上的男性中更为明显.
- 在老年男性中,SII可能是丸激素状态的潜在指标.
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