探索异常学脊椎病与各种多因素疾病之间的潜在关系:一个系统的范围审查
Kenney Ki Lee Lau1, Karlen Ka Pui Law2, Owen O Man Kam3
1Department of Orthopaedics and Traumatology, The University of Hong Kong, Pok Fu Lam, Hong Kong. kenneykl@connect.hku.hk.
Spine deformity
|April 9, 2025
概括
青少年异常学脊椎病 (AIS) 与各种健康问题有关,包括牙,消化,内分泌,肌肉骨和瘤等疾病. 这些关联表明潜在的共同遗传和系统途径有助于AIS.
科学领域:
- 整形外科 整形外科 整形外科
- 遗传学 是一个遗传学.
- 内分泌学 在内分泌学.
背景情况:
- 青少年异常学脊椎病 (AIS) 的病因是多因素的,涉及遗传和环境因素.
- 了解AIS并发症对于全面了解该疾病至关重要.
研究的目的:
- 审查和综合现有的关于与青少年异常学脊椎病 (AIS) 相关的并发症的文献.
- 探索AIS及其伴随性疾病之间的复杂关系.
主要方法:
- 在六个主要在线数据库 (AMED,CENTRAL,CINAHL,EMBASE,MEDLINE,WOS) 进行系统搜索.
- 包括对患有AIS和并发性疾病的人类初级研究.
- 由两个审查员进行独立选和数据提取.
主要成果:
- 九项研究符合资格标准,检查了伴随性疾病,如缺陷,中部早期青春期 (CPP),牙疾病,恶性造血性瘤 (MHN),关节疾病 (TMD) 和功能性胃肠道疾病 (FGD).
- 在AIS和牙异常,消化系统问题 (FGD),内分泌干扰 (CPP),肌肉骨失衡和瘤疾病 (MHN) 之间发现了显著的关联.
结论:
- AIS具有多因素和潜在的系统性质.
- 确定的并发症表明,在AIS发育中,有共同的遗传,荷尔蒙,神经肌肉和免疫路径.
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