身体功能变化与中风风险之间的关联:一项前性队列研究
Yulin Xie1, Yiling Lou1, Shen Huang1
1School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China.
Age and ageing
|April 9, 2025
概括
改善握力和平衡等身体功能可能会降低老年人中风风险. 这些变化对于识别高风险个体和预防中风至关重要.
科学领域:
- 老年学是一门学科.
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 身体功能变化与中风发病率之间的联系尚未得到充分理解.
- 评估身体功能变化对于预测中风风险至关重要.
研究的目的:
- 研究每年身体功能变化与中风发病率之间的关联.
- 探索身体功能变化和中风风险之间的剂量反应关系.
主要方法:
- 利用了2011-2020年中国健康与退休长度研究 (CHARLS) 7978名参与者的数据.
- 评估了绝对握力,相对握力,步行速度,起床时间和站立平衡的年度变化.
- 采用考克斯的比例危险模型和受限立方线分析来确定关联和剂量反应关系.
主要成果:
- 在71,714个人年内,共有549次中风事件被报告.
- 绝对握力,相对握力和站立平衡的改善与中风风险降低有关.
- 在步行速度或起床时间的变化与中风发生率之间没有发现显著的关联.
结论:
- 绝对握力,相对握力和站立平衡的更大改善与中年和老年人中风风险的降低有关.
- 客观的身体功能测量对于分层化中风风险和告知预防策略至关重要.
相关概念视频
01:27Regulation of Stroke Volume
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The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
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Cardiac output (CO), the amount of blood the heart pumps per minute, is a parameter in cardiovascular physiology determined by stroke volume and heart rate. Stroke volume, the amount of blood pushed from one of the ventricles per heartbeat, is influenced by preload, afterload, and contractility.
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Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
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