相关实验视频

Updated: May 15, 2025

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells
12:16

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells

Published on: October 16, 2018

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CD22 TCR工程T细胞在不引起炎症反应的情况下施加抗白血病细胞毒性

Kilyna A Nguyen1, Zhihui Liu2, John S Davies1,3

  • 1Center for Immuno-Oncology, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.

Science advances
|April 9, 2025
PubMed
概括

化学抗原受体 (CAR) -T细胞导致细胞因子释放综合征 (CRS),与T细胞受体 (TCR) -T细胞不同. 比较CD22CAR-T细胞和TCR-T细胞显示,CAR-T细胞诱导炎症,突出了TCRs用于更安全的癌症疗法.

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Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography09:34

Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography

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