相关实验视频

Updated: May 5, 2026

Protocol for Isolation of Primary Human Hepatocytes and Corresponding Major Populations of Non-parenchymal Liver Cells
08:47

Protocol for Isolation of Primary Human Hepatocytes and Corresponding Major Populations of Non-parenchymal Liver Cells

Published on: March 30, 2016

36.9K

在体外肝脏模型用于毒理学研究

Ichiro Fukunaga1, Takanori Takebe2

  • 1Center for Genomic and Regenerative Medicine, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo, 113-8431, Japan.

Drug metabolism and pharmacokinetics
|April 9, 2025
PubMed
概括

药物诱导性肝损伤 (DILI) 研究正在转向先进的3D肝器官. 这些模型为毒理学评估提供了与动物试验更相关的人类替代方案.

关键词:
3D文化是一个3D文化.迪利迪利 迪利 迪利 迪利这是一种HepG2型肝炎.这就是HepaRGG.人类肝脏的有机体.在体外肝脏模型.多能干细胞是一种多能干细胞.主要肝细胞主要是肝细胞.

更多相关视频

Advanced 3D Liver Models for In vitro Genotoxicity Testing Following Long-Term Nanomaterial Exposure08:25

Advanced 3D Liver Models for In vitro Genotoxicity Testing Following Long-Term Nanomaterial Exposure

Published on: June 5, 2020

6.6K
Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro11:06

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro

Published on: January 31, 2022

4.2K

相关概念视频

Clearance Models: Physiological Models01:09

Clearance Models: Physiological Models

Drug clearance is a critical pharmacokinetic process involving the irreversible removal of drugs from the body through various organs over a specified time period. Physiological models are indispensable in determining organ-specific clearance, defined by the proportion of the drug eliminated per unit of time from the organ's blood volume.
The organ's clearance rate depends on the blood flow to the organ and the extraction ratio (E). The extraction ratio describes the organ's...
472