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Updated: May 20, 2025

A Direct, Early Stage Guanidinylation Protocol for the Synthesis of Complex Aminoguanidine-containing Natural Products
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设计,合成和生物评估C1-烯胺衍生物C1-烯胺衍生物

Su-Mei Wang1, Wan-Sheng Ji2, Long-Jiang Chen3

  • 1Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China; School of Chemistry, Southwest Jiaotong University, Chengdu 610031, China.

Fitoterapia
|April 9, 2025
PubMed
概括

新的胺衍生物在阿尔茨海默病 (AD) 方面显示出有前途. 化合物4k有效地抑制乙胆酶 (AChE) 和丁胆酶 (BChE),同时保护大脑细胞,表明作为多功能AD治疗的潜力.

关键词:
这是一种ACHE抑制剂.阿尔茨海默氏症的疾病是阿尔茨海默氏症.这是一种BCHE抑制剂.加兰他胺是一种胺.神经保护性活动神经保护性活动

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