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Updated: May 15, 2025

Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C
07:13

Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C

Published on: March 25, 2016

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巨细胞迁移抑制因子有助于跨妊娠阶段实验性妊娠疟疾的不良结果

Andrea Tatiana Durán-Rodriguez1, Marcos Paulo O Almeida1, Flávia Batista Ferreira1

  • 1Laboratory of Immunopathology, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.

The American journal of pathology
|April 9, 2025
PubMed
概括

向巨细胞迁移抑制因子 (MIF) 在妊娠疟疾小鼠模型中改善了怀孕结果. 在MIF缺乏的小鼠中观察到减少胚胎再吸收和更好的胎儿发育,这表明治疗潜力.

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相关概念视频

Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
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