电子健康干预措施和与代谢功能障碍相关的脂肪性肝病患者:系统性审查和元分析
Yousuf Zafar1, Muhammad Umer Sohail2, Muhammad Saad2
1Department of Medicine, University of Mississippi University Hospital, Jackson, Mississippi, USA.
BMJ open gastroenterology
|April 9, 2025
概括
电子健康干预措施显著改善了与代谢功能障碍相关的脂肪性肝病 (MASLD) 的结果,包括减肥和肝酶. 需要进一步的研究来证实长期益处.
科学领域:
- 肝病学和代谢健康
- 数字健康干预措施 数字健康干预措施
- 公共卫生和肥胖管理
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD) 是与肥胖大流行相关的日益严重的全球健康问题.
- 减肥对于改善MASLD结果至关重要,但数字健康干预措施的有效性仍然不清楚.
- 电子健康干预为MASLD管理提供了潜在的途径,解决了可访问性和可扩展性的挑战.
研究的目的:
- 系统地评估电子卫生干预措施的有效性,与对MASLD患者的标准护理相比.
- 评估电子健康对关键健康指标的影响,包括体重,肝酶和身体成分.
- 综合当前关于数字健康在管理MASLD中的作用的证据.
主要方法:
- 一个系统的审查和元分析,遵循PRISMA指南.
- 搜索了PubMed,Cochrane Central和Embase数据库,截至2024年4月26日.
- 包括英语双臂临床试验,比较电子健康干预措施 (应用程序,可穿戴设备) 与MASLD患者的标准护理.
主要成果:
- 分析了10项涉及39.3-57.9岁的3-24个月以上的研究.
- 电子健康干预措施显著降低了AST (SMD: -0.35) 和ALT (SMD: -0.38) 水平.
- 通过电子健康干预,体重减轻 (SMD: -0.38) 和BMI (SMD: -0.37) 显著改善.
结论:
- 电子健康干预措施对MASLD患者有显著的益处,改善肝酶,体重和BMI.
- 这些数字工具在管理MASLD方面表现有前途,MASLD是一种由肥胖流行病加剧的疾病.
- 建议使用更大的队列进行更长的后续研究,以验证MASLD护理中电子健康干预措施的持续有效性.
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