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Updated: May 15, 2025

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Assessment of Child Anthropometry in a Large Epidemiologic Study
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儿童肥胖的风险因素和预测:当前状况和未来的前景
Shiori Minabe1,2, Yoichi Sutoh1,2, Yayoi Otsuka-Yamasaki1,2
1Division of Biomedical Information Analysis, Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Yahaba 028-3694, Japan.
Endocrine journal
|April 9, 2025
概括
儿童肥胖是一个全球性的健康问题. 通过以家庭为中心的环境,遗传和表观遗传因素,早期识别有风险的儿童对于预防至关重要.
科学领域:
- 儿科 儿科 儿科
- 公共卫生 公共卫生
- 遗传学 是一个遗传学.
背景情况:
- 儿童肥胖是一个重要的全球健康问题,患病率不断上升.
- 它与非传染性疾病和长期健康问题有关.
- 风险因素涉及复杂的环境,遗传和表观遗传相互作用.
研究的目的:
- 总结儿童肥胖的环境,遗传和表观遗传风险因素.
- 审查与儿童肥胖相关的日本地区因素.
- 引入儿童肥胖风险预测模型的进步.
主要方法:
- 对环境,遗传和表观遗传风险因素的审查.
- 分析日本的独特情况和区域因素.
- 探索机器学习的进步和用于风险预测的表观遗传学标记.
主要成果:
- 儿童肥胖风险受到家庭环境,遗传学和表观遗传学 (例如,DNA甲基化) 的影响.
- 早期识别有风险的儿童和家庭对于干预至关重要.
- 目前的预测模型缺乏临床实施,需要更高的准确性和验证.
结论:
- 有效的儿童肥胖预防需要准确的,经过验证的预测模型,考虑到人口特异性的因素.
- 整合环境,遗传和表观遗传数据是关键.
- 需要进一步的研究来开发和实施强大的风险预测工具.
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