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Updated: Jun 10, 2026

Imaging Amyloid Tissues Stained with Luminescent Conjugated Oligothiophenes by Hyperspectral Confocal Microscopy and Fluorescence Lifetime Imaging
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Imaging Amyloid Tissues Stained with Luminescent Conjugated Oligothiophenes by Hyperspectral Confocal Microscopy and Fluorescence Lifetime Imaging

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YOPRO-1:一种基于的分子旋转探头,用于粉样纤维素检测

Sailee D Shahane1, Niyati H Mudliar1, Bhavya R Chawda1,2

  • 1SVKM's Shri C. B. Patel Research Centre, Vile Parle, Mumbai, Maharashtra 400056, India.

ACS applied bio materials
|April 9, 2025
PubMed
概括

一个新的光探测器YOPRO-1在复杂的生物样本中提供了卓越的粉样纤维的检测. 这一进步有助于早期诊断神经退行性疾病,如阿尔茨海默氏症.

关键词:
在YOPRO-1中使用.粉样蛋白纤维的纤维.氨酸染料是一种素染料.外在光传感器外在光传感器分子旋转器探针探针

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Author Spotlight: Non-Invasive Imaging of Complex Bio-Structures Using Polarization-Sensitive Two-Photon Microscopy05:54

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相关概念视频

Amyloid Fibrils03:03

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining, normally used to...
Amyloid Fibrils03:03

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining, normally used to...