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对含有基的分子进行超分子对接结构的确定

Yitao Wu1,2, Le Shi1,2,3, Lei Xu4

  • 1Stoddart Institute of Molecular Science, Department of Chemistry, Zhejiang University, Hangzhou, People's Republic of China.

Nature
|April 9, 2025
PubMed
概括

自然产品和药物中的柔性链阻碍了X射线结晶学. 支柱[5]甲基-有机框架 (MOF) 能够实现超分子对接,减少运动,并为具有挑战性的分子提供单晶X射线衍射 (SCXRD) 结构确定.

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