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在重症监护室获得的直肠殖民和随后感染的耐卡巴胺细菌:一个横截面研究

Suzan Şahin¹, Gülfem Akengin Öcal², Elif Bombacı³

¹Department of Infectious Diseases and Microbiology, Dr. Lütfi Kırdar Kartal City Hospital, 34865, Cevizli, Kartal, Istanbul, Türkiye. drsuzansahin@yahoo.com.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

|April 9, 2025

概括

近10.5%的ICU患者获得了耐卡巴胺细菌 (CRB) 殖民,近一半患有CRB感染. 这凸显了尽管有监测工作,但医院感染的持续威胁.

科学领域:

传染性疾病传染性疾病
关键护理医学关键护理医学
微生物学微生物学

背景情况:

由抗卡巴胺细菌 (CRB) 引起的鼻腔感染构成了全球重大健康挑战.
在重症监护室 (ICU) 中对CRB定居的常规监测对于了解传播和感染风险至关重要.

研究的目的:

确定ICU获得的胃肠道殖民化与CRB的发病率和临床结果.
通过直肠抽样监测检测到的殖民后CRB感染发展的速度.

主要方法:

从2020年1月到2022年12月入住ICU的成年患者的回顾性研究.
在至少72小时住院的患者中,对CRB定居的直肠拭子培养物的分析.
对被殖民患者的临床结果的评估,包括感染的发展,ICU停留和死亡率.

主要成果:

在4673名符合条件的患者中,观察到CRB定居的患病率为10.5%.
克莱布西拉肺炎是最常见的CRB物种 (41.8%),其次是Acinetobacter baumannii (32.3%).
几乎一半的殖民患者 (48.7%) 患上了CRB感染,与死亡率增加和长时间的ICU停留有关.

结论:

尽管采取了预防措施,但很大一部分ICU患者获得了CRB定居点.
CRB殖民是发展CRB感染的重要危险因素,导致不良的临床结果.
加强监测和感染控制策略对于减轻ICU中CRB的影响至关重要.

关键词:

耐卡巴胺的细菌可以抵抗卡巴胺.在ICU获得的感染.结直肠殖民化的殖民化检查直肠的抽样.

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