无气体vNOTES与良性妇科疾病的传统vNOTES:一种随机对照临床试验
Yanjun Wang1, Kai Liu2, Zhaolin Gong1
1Department of Gynecology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 611731, China.
BMC anesthesiology
|April 9, 2025
概括
无气体的经阴道自然孔透光内镜手术 (G-vNOTES) 与传统的vNOTES (T-vNOTES) 没有表现出血液动力学上的好处. G-vNOTES的转化率更高,这表明它需要更多的外科医生经验.
科学领域:
- 最少侵入性的妇科手术
- 手术创新 在外科创新.
- 患者的治疗结果.
背景情况:
- 通过阴道自然孔的透光内镜手术 (vNOTES) 提供了潜在的好处,通过避免肺.
- 关于无气体vNOTES (G-vNOTES) 和其比较结果的研究有限.
- 这项研究解决了对比G-vNOTES与传统vNOTES (T-vNOTES) 的证据需求.
研究的目的:
- 为了比较G-vNOTES与T-vNOTES的血液动力学概况和临床结果.
- 评估G-vNOTES在患有良性妇科疾病的患者的安全性和有效性.
主要方法:
- 一项随机对照试验,涉及120名患有良性妇科疾病的患者.
- 患者被分配到G-vNOTES (n=60) 或T-vNOTES (n=60) 中.
- 主要结局:手术内生命体征;次要结局:转换率,手术指标,疼痛,恶心和恢复指标.
主要成果:
- 在G-vNOTES和T-vNOTES组之间,手术内血动力学性能没有显著差异.
- 与T-vNOTES组 (5.26%) 相比,G-vNOTES组 (16.95%) 的转换率明显高于T-vNOTES组 (5.26%).
- 在二次结果中没有观察到其他显著差异.
结论:
- 与传统的vNOTES相比,无气体vNOTES在手术期间的血液动力稳定性方面没有优势.
- 在G-vNOTES中,手术转换率的增加可能是由于手术现场暴露较差.
- 对于经验丰富的外科医生来说,G-vNOTES可能更适合.
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