开发一个核心的结局设置为acetabular骨折:一个系统的审查 (第一部分)
Denise Schulz1,2, Catharina Gaeth3,4, Martin C Jordan3,5
1Department of Orthopaedics and Traumatology, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany. Denise.Schulz@med.uni-duesseldorf.de.
Systematic reviews
|April 9, 2025
概括
这项研究确定了手术骨骨折治疗中的266个独特结果,突出了需要标准化核心结果集 (COS) 来提高研究可比性.
科学领域:
- 整形外科手术 整形外科手术
- 创伤护理 创伤护理
- 临床研究方法论 临床研究方法论
背景情况:
- 对骨骨折的手术治疗研究显示出结果的异质性,阻碍了研究的可比性和知识合成.
- 目前缺乏用于手术治疗骨骨折的标准化核心结果集 (COS).
- 这项研究旨在识别和分类现有关于手术治疗骨骨折的文献中报告的结果.
研究的目的:
- 系统地识别和目录所有临床研究报告的结果,调查骨骨折的手术治疗.
- 为开发骨骨折手术的核心结果集 (COS) 提供基础.
- 为了解决在骨骨折研究中测量结果的异质性.
主要方法:
- 在三个数据库和两个临床试验注册表中进行系统的文献搜索 (2022年11月15日更新).
- 纳入标准:骨成熟的个体 (≥16岁) 具有孤立的骨骨折,经过手术治疗.
- 排除标准:多创伤,病态骨折,额外的骨盆骨折,非手术治疗或未成年人. 结果被分组并使用有效性试验 (COMET) 中的核心结果措施分类法分类.
主要成果:
- 193项研究产生了2581个结局,在分组后产生了266个独特的结局.
- 在所有研究中都没有报告任何单一的结局;最常见的是疼痛,独立行走,运动范围,减少质量和异型骨化 (在≥60%的研究中).
- 结果命名,定义,测量时间和使用的仪器存在显著差异,仅在一项研究中报告了105个结果.
结论:
- 在手术治疗骨骨折的研究中,各种各样的结果被不一致地测量.
- 确定的结果涵盖了COMET分类学中的所有五个核心领域和25个领域.
- 这些发现将为使用Delphi方法进行骨骨折手术的COS的后续开发提供信息.
更多相关视频
09:51The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve
Published on: September 7, 2022
2.5K
07:45The Use of Mixed Reality in Custom-Made Revision Hip Arthroplasty: A First Case Report
Published on: August 4, 2022
3.3K
相关概念视频
01:27Fractures: Bone Repair
2.8K
Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
2.8K
01:19Standards of Care II
627
Nurses bear specific legal responsibilities under several federal statutes, including:
627
01:22Standards of Care I
660
Federal statutes profoundly impact nursing practice, providing critical guidelines to ensure patient care is equitable, accessible, and of the highest quality. The following laws address distinct aspects of healthcare provision and patient rights:
660
01:16Bones of the Lower Limb: Femur and Patella
2.0K
The femur is the body's longest and strongest bone spanning the thigh region. Its head articulates with the acetabulum of the hip bone to form the hip joint. A minor indentation on the medial side of the femoral head, called the fovea capitis, serves as the site of attachment for the ligament of the head of the femur. This weak ligament spans the femur and acetabulum and supports the hip joint. The narrowed region below the head is the neck of the femur. The inclination angle between the...
2.0K