使用心脏磁共振成像和对心脏再同步治疗的反应进行组织表征
Se-Eun Kim1, Jaewon Oh2, Yoo Jin Hong3
1Department of Cardiology, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.
概括
心脏磁共振成像组织参数预测非缺血性心肌病的心脏再同步治疗反应. 较低的晚期加多增强,细胞外体积和T2值表明更好的结果.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 生物标志物 生物标志物
背景情况:
- 心脏磁共振 (CMR) 成像有助于心肌病的风险分层.
- 使用CMR进行组织表征提供了预后见解.
研究的目的:
- 评估CMR衍生组织参数对心脏再同步治疗 (CRT) 响应的预测值.
- 评估接受CRT的非缺血性心肌病症 (NICM) 患者的结果.
主要方法:
- 在CRT前的101名NICM患者中,对CMR数据 (晚期加多增强,T1,T2,细胞外体积) 的回顾性分析.
- 对CRT响应者与非响应者之间的参数进行比较.
主要成果:
- 与非响应者相比,CRT响应者 (71.3%) 的LGE负担,本地T1,T2和ECV显著较低.
- LGE负荷 ≤ 20%,ECV ≤ 34%,T2 ≤ 45 ms 独立预测了良好的CRT响应和有利的结果.
结论:
- 基于CMR的组织特征有效预测NICM患者的CRT反应.
- 这些参数提供了超越传统预测器的预后价值.
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