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在无效食道运动的长期预后和预后因素
Yassir Al-Oleiw1, Daghan Demir1, Axel Josefsson1
1Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Journal of neurogastroenterology and motility
|April 10, 2025
概括
无效的食道机动性往往导致长期的消化不良和胸痛. 在人体测量过程中使食道周平静正常化可能会预测缺食症的更好结果,但不是其他症状.
科学领域:
- 胃肠病学 胃肠病学
- 食道运动障碍 食道运动障碍
- 诊断力测仪的诊断力测仪
背景情况:
- 无效食道运动 (IEM) 是一种常见的食道周立体障碍.
- 症状包括消化不良,胸痛和胃烧,影响生活质量.
- 在IEM中挑性测试的长期预后和预测价值需要进一步评估.
研究的目的:
- 评估患有无效食道运动的患者的长期预后.
- 为了确定高分辨率食道测量时的挑性测试是否可以预测预后.
主要方法:
- 对高分辨率食道力度测试 (2015-2018) 的回顾性分析.
- 在基线和长期随访 (中位数为39个月) 评估症状 (腹,胸痛,反流).
- 在固体玻尿酸吞和快速饮料挑战中评估食道周围平衡的正常化.
主要成果:
- 11.6%的患者有IEM;33名患者组成了最终的队列.
- 在随访时,42%的人患有消化不良,25%的胸痛,46%的反流症状.
- 固体玻尿酸吞的正常化运动与较少的消化不良相关 (P=0.012),但没有胸痛或反流.
结论:
- 患有IEM的患者经历了持续的长期食道症状.
- 挑性测量测试显示,在预测IEM的长期发育障碍的预后方面有潜力.
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