相关实验视频

Updated: Jun 12, 2025

Efficient and Scalable Production of Full-length Human Huntingtin Variants in Mammalian Cells using a Transient Expression System
10:52

Efficient and Scalable Production of Full-length Human Huntingtin Variants in Mammalian Cells using a Transient Expression System

Published on: December 10, 2021

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改变的亨廷丁-染色素相互作用预测了亨廷顿病的转录和表观遗传变化

Jocelynn R Pearl1,2, Amol C Shetty3, Jeffrey P Cantle4,5

  • 1Institute for Systems Biology, Seattle, WA 98109, USA.

Disease models & mechanisms
|April 10, 2025
PubMed
概括

亨廷丁蛋白 (HTT) 结合了特定的基因组位置,影响了条纹体中的基因表达. 减少HTT结合与亨廷顿病 (HD) 中基因活性变化相关,这表明在转录失调中发挥了作用.

关键词:
染色是一种染色素.表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.在狩猎中寻找.亨廷顿病就是亨廷顿病.

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