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骨肉瘤治疗后的晚期和长期影响:一个范围审查

Kaainat Khan¹, Kathleen Kane², Zoe Davison²

¹Biomedical Research Centre, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, United Kingdom.

Journal of bone oncology

|April 10, 2025

概括

骨肉瘤幸存者需要专门的长期随访,以检查晚期影响,如二次癌症和器官损伤. 目前的护理不一致,使许多患者没有足够的支持来解决这些严重的健康问题.

科学领域:

在瘤学瘤学.
幸存者护理幸存者护理
医学研究医学研究

背景情况:

骨肉瘤 (例如,尤文肉瘤,骨肉瘤) 的治疗方法 (化疗,手术,放射治疗) 具有显著的毒性和改变生命的后果.
在癌症监测之外,对于晚期和长期影响的治疗后随访不一致地提供给前患者.
事证据表明,许多骨肉瘤幸存者因随访护理变化而面临晚期影响,支持有限.

研究的目的:

进行范围审查,以经验性地确定骨肉瘤治疗晚期和长期影响的知识差距.
提供对同行评审文献的概述,报告骨肉瘤幸存者经历的晚期和长期影响.

主要方法:

根据JBI范围审查网络的指导方针进行了范围审查.
在多个数据库 (Medline,Cochrane,EMBASE,CINAHL,PsycINFO,Proquest,Web of Science) 中进行了广泛的文献搜索.
包括74篇同行评审文章,主要是追溯研究,追踪时间长达20年.

主要成果:

发现的主要身体晚期和长期影响包括二次恶性瘤,心脏和毒性,骨矿物质密度下降和运动神经病变.
与癌症相关的疲劳也被认为是需要关注的显著长期影响.
随访护理可能需要延长几十年,特别是随着幸存者人口的不断增长.

结论:

需要专门的后续服务来管理骨肉瘤治疗的各种晚期和长期影响.
这些发现为未来的服务映射提供了证据基础,并为幸存者护理提供了扩展的临床建议.
解决这些长期影响对于改善骨肉瘤幸存者的生活质量至关重要.

关键词:

骨肉瘤骨肉瘤是一种骨肉瘤.癌症癌症癌症癌症化疗化疗是一种化学疗法.晚期影响后期影响幸存者的生存方式

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