相关实验视频
Updated: May 15, 2025

Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
巴西克罗恩氏病手术和住院率的时间趋势:基于人口的研究
João Augusto Dos Reis Guerra1, Daniela Oliveira Magro2, Claudio Saddy Rodrigues Coy2
1Colorectal Surgery Unit, Catholic University of Paraná, IBD Outpatient Clinics, Curitiba, Brazil.
尽管克罗恩氏病 (CD) 诊断的增加和巴西生物使用的增加,但住院和手术减少. 这表明CD患者的管理得到了改善,即使疾病负担越来越大.
科学领域:
- 胃肠病学 胃肠病学
- 公共卫生 公共卫生
- 药物经济学 药物经济学
背景情况:
- 生物疗法显著影响了炎症性肠病 (IBD) 管理.
- 关于生物疗法的有效性在降低克罗恩病 (CD) 外科手术率方面仍然存在争议.
- 了解CD治疗和结果的时间趋势对于公共卫生政策至关重要.
研究的目的:
- 分析巴西CD患者手术和住院率的时间趋势.
- 为了将这些趋势与关键药物的分发模式相关联:阿扎西奥普林 (AZA),因弗力西马布 (IFX) 和阿达利穆马布 (ADA).
- 评估生物疗法对巴西国家医疗保健系统中CD管理结果的影响.
主要方法:
- 一项回顾性观察性研究,利用2012年至2022年的数据.
- 对人口统计数据,药物发行和国际疾病分类 (ICD) 关于CD相关住院和手术的代码的分析.
- 年平均百分比变化 (AAPC) 的计算,以评估疾病流行,治疗,住院和手术程序的时间趋势.
主要成果:
- 在2012年至2022年期间,CD诊断增加了288.07%.
- 绝对使用AZA,IFX和ADA增加,但AZA患者的比例显著下降 (-57.28%).
- 尽管CD病例增加和生物可用性增加,但CD患者中住院 (-59.29%) 和手术 (-55.08%) 的比例下降.
结论:
- 在巴西,CD患者中住院和手术的比例有所下降.
- 这种下降发生在CD患病率大幅增加和绝对生物分发的同时.
- 调查结果表明,在公共卫生保健系统内,CD管理和治疗疗效的潜在改善.
更多相关视频
03:47Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
Published on: November 1, 2024
00:08Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
Published on: August 24, 2019
相关概念视频
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids