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Updated: May 15, 2025

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颗粒激活骨细胞连接素43,通过JAK-STAT途径诱导氧化应激和骨质结晶形成

Jiawei Ouyang1, Hao Chai1,2, Chunguang Sun1

  • 1Department of Orthopedics, The Second Affiliated Hospital of Soochow University, Suzhou, China.

Antioxidants & redox signaling
|April 10, 2025
PubMed
概括

骨细胞中的Connexin 43 (Cx43) 通过激活JAK-STAT通路并增加氧化应激,驱动周围假肢骨解. 减少Cx43表达或阻断这种途径可以减轻骨的再吸收,并改善骨重塑.

关键词:
在JAK-STAT路径上.连接器 43 连接器 43骨质细胞生成 (osteoclastogenesis) 是一个过程.这些骨质细胞是骨质细胞.氧化应激是一种氧化应激.

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