大人的心房功能障碍和心房节律失常之间的关系 丰田息:心房应变成像的作用
Sara ElZalabany1, Amr Moustafa1, Ali Ali1
1Department of Cardiovascular Medicine Mayo Clinic Rochester MN USA.
Journal of the American Heart Association
|April 10, 2025
概括
通过心房张力成像检测到的心房功能障碍在Fontan患者中很常见,并预测心律不整. 节律控制疗法可能更好地适用于心房压力减轻的患者.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 遗传性心脏病是一种先天性心脏病.
背景情况:
- 大心律不整是常见的,并且在Fontan息中具有预后影响.
- 心房张力成像可以检测心房功能障碍,心房失常的危险因素.
- 心房张力成像在Fontan患者心房失常风险分层化中的作用仍未研究.
研究的目的:
- 为了研究肺静脉心房应变与新发作或复发性心房失常症在成年人与Fontan息之间的关联.
- 通过心房张力成像在这个人群中评估心房功能障碍的患病率.
主要方法:
- 对于404名没有先前心房失常史的成年人进行了回顾性研究,他们接受了Fontan息治疗.
- 使用斑点跟踪回声心脏成像进行了心房张力成像.
- 从基线到随访期间,新发病和复发性心房律不整的病例被跟踪.
主要成果:
- 在81%的患者中,心房水库应变评估是可行的.
- 大心脏功能障碍 (大心脏储菌株<28%) 的患病率很高 (89%).
- 减少心房储应变 (<15%) 与新发病 (aHR 1.59) 和复发 (aHR 2.01) 心房失常症的风险增加有关.
结论:
- 在Fontan患者中,心房功能障碍很常见,并且与心房失常症有显著的关联.
- 减少心房应变可以识别出患心房律乱的风险较高的患者.
- 节律控制疗法表现出对复发性心律失常的保护作用,这表明在心房压力减轻的患者中可能更喜欢它.
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